Sino Biological, Inc. (Shenzhen Stock Exchange: 301047.SZ) announced the launch of its XPressMAX™ Cell-Free Protein Synthesis Kit (Cat#: CFKIT02), a new tool designed to accelerate AI-powered high-throughput screening for antibody drug discovery. The kit leverages cell-free protein synthesis technology to produce target proteins and antibodies rapidly in vitro, bypassing the limitations of traditional cell-based expression systems. This integration with AI screening platforms aims to significantly reduce development timelines and costs.
The XPressMAX™ kit, based on an E. coli lysate fully supplemented with transcription and translation components, enables direct protein synthesis from plasmid or PCR templates. It is specifically designed for antibody drug discovery, supporting rapid expression and validation of VHH, scFv, Fab, and miniproteins. Sino Biological has established a high-throughput cell-free expression platform that can validate over 2,000 scFv/VHH molecules in 3-4 weeks, matching AI's rapid iteration capabilities.
Key highlights of the XPressMAX™ kit include ultra-fast synthesis completed in just 3 hours, a success rate greater than 99%, and support for complex disulfide bonding without additional enhancers, ensuring native folding and bioactivity. Dr. Rob Burgess, Chief Business Officer at Sino Biological US, Inc., stated, 'Our XPressMAX™ is a significant advancement in research tools and reagents for next-generation therapeutic discovery. By combining rapid, reliable protein expression with intelligent screening, we are helping our partners compress antibody discovery timelines without compromising quality.' Dr. Jie Zhang, Sino Biological’s General Manager, added, 'AI is revolutionizing antibody screening, but it demands expression systems that can match its speed and throughput. XPressMAX™ achieves rapid, high-success expression of challenging proteins in as little as 3 hours.'
Researchers can visit www.sinobiological.com to explore more about the XPressMAX™ kit or request a free sample. Additional information is available on the product page at https://www.sinobiological.com/other-products/cell-free-protein-synthesis-system-cfkit02 and the cell-free expression platform at https://www.sinobiological.com/category/solutions/cell-free.
