Creative Diagnostics, a leading manufacturer and supplier of antibodies, antigens and assay kits, has announced its new Hantavirus Research Reagents and Products to support hantavirus research and diagnostic assay development. This comprehensive catalog is designed to help academic researchers, biopharmaceutical companies, and industrial organizations accelerate the development of diagnostic assays and therapeutic interventions targeting dangerous rodent-borne orthohantaviruses.
Hantaviruses are emerging zoonotic pathogens belonging to the Bunyaviridae family, classified as Category A pathogens by the US Centers for Disease Control and Prevention (CDC). They pose a serious threat to human health, causing haemorrhagic fever with renal syndrome (HFRS) or hantavirus cardiopulmonary syndrome (HCPS), both of which are highly fatal. Transmission occurs via aerosols containing excreta from infected rodent hosts. The virus has a tripartite negative-strand RNA genome encoding the nucleocapsid protein (N), envelope glycoproteins Gn and Gc, and RNA-dependent RNA polymerase (RdRp). The N protein plays a crucial role in protecting genomic RNA and facilitating transcription and replication.
Currently, no antiviral therapies or vaccines are available for hantavirus-associated diseases. A deeper understanding of the molecular mechanisms of the hantavirus life cycle could identify targets for antiviral therapy. Given the high case-fatality rate, developing an effective vaccine is imperative. Early clinical manifestations often resemble common respiratory illnesses, underscoring the urgent need for sensitive, reliable diagnostic tools for early differential diagnosis.
To address these challenges, Creative Diagnostics offers a range of reagents covering multiple strains, including Hantavirus, Puumala virus (PUUV), Seoul virus (SEOV), and Sin Nombre virus (SNV). The product line includes recombinant hantavirus antigens for assay development; high-affinity monoclonal and polyclonal antibodies validated for capture and detection across platforms such as Western blot, flow cytometry, immunohistochemistry, and surface plasmon resonance; and supporting reagents for ELISA and rapid immunoassay research.
For detailed product specifications, volume pricing, or to browse the complete list of available viral solutions, visit the official product portal at https://www.creative-diagnostics.com/hantavirus.htm.
